In January 2007, Evangelos D. Michelakis and fellow researchers at the University of Alberta which is located in Edmonton, Alberta, Canada, released a study inwhich they tested dichloroacetate (CHCl2COOH) on in vitro cancer cell lines[cells which are artifically maintained in a laboratory] in a rat. It was discovered that dichloroacetate restored mitochondrial function(production and regulation of energy) within the cell which in turn restored Programmed cell-death (PCD) which allows for cell suicide. Specifically Apoptosis or Type I cell-death is re-activated by dichloroacetate. Cells which are not diseased or damaged will not be activated to self-terminate thus no damage is incured upon the organism.
"mitochondria are so sensitive to DCA that just 5 minutes of exposure reactivates them for 48 hours"(Michelakis,2007)
Average recommended Dosage: 10 mg/kg to 15 mg/kg per day.
Instructions: Mix Dosage in water and drink twice a day for several months.
Acute toxicity: Oral LD50 in rats is 4480 mg/kg and 5520 mg/kg for mice.
Linkz:
http://www.sanger.ac.uk/genetics/CGP/CellLines/
http://en.wikipedia.org/wiki/Dichloroacetate
http://www.thedcasite.com/
http://www.thedcasite.com/DCA%20(Cancer%20Cell).pdf
http://www.thedcasite.com/dca_dosage.html
http://www.depmed.ualberta.ca/dca/
http://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20070116/cancer_dca_070116/20070116
http://www.depmed.ualberta.ca/dca/vid1.htm
http://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20070120/DCA_feature_070121/20070122?hub=Health
http://ptcl.chem.ox.ac.uk/MSDS/DI/dichloroacetic_acid.html
http://www.newscientist.com/article.ns?id=dn10971
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